Dec 8


Day 1



9:00 am - 18:00 pm


Meeting    register,  Xiamen  University    International    Academic  Exchange Center,   Xiangan Campus


Dec 9


Day 2


9:00 -9:10 am


Opening Remark


Session 1


Session Chair: Steven Kliewer



9:10 - 10:00 am


Opening Keynote Lecture:

Ming-Jer Tsai, Baylor College of Medicine, USA.

Role of COUP-TFII in prostate cancer and muscular dystrophy


10:00 –10:30 am


Group photo and Coffee/Tea Break


Session 2


Session Chair: Steven Kliewer



10:30 –11:10 am


Steven Kliewer, UT Southwestern Medical Center at Dallas, USA.

Metabolic stress hormone FGF21: from pharmacology to physiology



11:10 – 11:40 am


Sophia Y. Tsai, Baylor College of Medicine, USA.

COUP-TFII in heart development and heart failure



11:40 – 12:10 am


Youfei Guan, Dalian Medical University, China.

Nuclear   receptor   regulatio o collectin duct   water     an sodium homeostasis.


12:10 – 14:00 pm




Session 3


Session Chair: Eric Xu



14:00 - 14:30 pm


Eric Xu, Van Andel Research Institute, USA.

Structures and ligand regulation of orphan nuclear receptors



14:30 - 15:00 pm


Yong Li, Xiamen University, China.

Farnesoid    X    receptor  modulators:  from  structure  to  pharmaceutical







15:00 - 15:30 pm


Yong Xu, Guangzhou Institute of Biomedicine and Health, CAS, China. Targeting nuclear receptors and related epigenetics proteins in prostate cancer


15:30 - 15:50 pm


Coffee/Tea Break



15:50 -16:20 pm


Chundong Yu, Xiamen University, China.

Histone demethylase JMJD2D in colorectal cancer progression



16:20 -16:50 pm


Jongsook Kim Kemper, University of Illinois at Urbana-Champaign, USA. Epigenetic control of lipid metabolism and autophagy by JMJD3 histone demethylase



16:50 -17: 20 pm


Zhou Songyang, Sun Yat-sen University, China.

Telomere protection in aging and cancer




17:20 -17:35 pm


Short talk 1

Shaobing O. Zhang, Capital Normal University, China.

Specific regulation of thermosensitive lipid droplet fusion by a nuclear hormone receptor pathway


17:35 – 17:50 pm


Short talk 2

Jun Yan, Nanjing University, China.

Triptolide inhibit th A pathway     t suppress     th proliferatio of enzalutamide resistant prostate cancer cells



17:50 -20:00 pm




Dec     10


Day 3


Session 4


Session Chair: David Moore


9:00 – 9:30 am


David Moore, Baylor College of Medicine, USA.

Regulation of liver energy balance by nutrient-sensing nuclear receptors


9:30 – 10:00 am


Wendong Huang, City of Hope, USA.

Bile acid receptors as the molecular targets of bariatric surgery


10:00 – 10:30 am


Li Wang, University of Connecticut, USA.

Nuclear receptor SHP in LncRNA regulation and liver disease




10:30 – 10:50 am


Coffee/Tea Break


10:50 – 11:20 am


Wen Xie, University of Pittsburgh, USA.

A     sulfotransferase-mediated    negative     feedback     that    controls     the gluconeogenic activity of HNF4α


11:20 – 11:50 am


Vincent Giguère, University of McGill, Canada.

Nuclear receptor-mTOR interactions in the control of cellular metabolism


11:50 – 12:05 am


Short talk 3

Wen Liu, Xiamen University, China.

Crosstalk between estrogen receptor and 2OG-oxygenase JMJD6 in breast carcinogenesis


12:10- 14:00 pm




Session 5


Session Chair: Xiaokun Zhang


14:00-14:30 pm


Xiaokun Zhang, Xiamen University, China.

Nur77 regulation of mitochondrial activity


14:30 - 15:00 pm


Qiao Wu, Xiamen University, China.

Nuclear  receptor    Nur77  suppresses  hepatocellular  carcinoma  through regulation of PEPCK1 sumoylation



15:00 - 15:30 pm


Meng Wang, Baylor College of Medicine, USA.

Microbe-host    mitochondria  interaction  in    regulating  lipid    metabolism through NR5A-hedgehog signaling


15:30 - 15:50 pm


Coffee/Tea Break


Session 6


Session Chair: Dawang Zhou



15:50 -16:20 pm


Dawang Zhou, Xiamen University, China.

Hippo signaling in liver cancer development



16:20-16:50 pm


Jun Luo, Johns Hopkins University, USA

Androgen receptor variants: from discovery to patient benefit




16:50 -17:40 pm


Closing Keynote Lecture:

Donald McDonnell, Duke University, USA

Identification of targetable proteins and processes downstream of steroid receptors in breast and prostate cancer




17:40-17:50 pm


Close remark

Dawang Zhou, Xiamen University, China.


18:30 - 20:30 pm


Conference Banquet




Dec     11


Day 4